Comments on: Neurogenesis and the septotemporal axis at #SFN11 http://www.functionalneurogenesis.com/blog/2011/11/neurogenesis-and-the-septotemporal-axis-at-sfn11/?utm_source=rss&utm_medium=rss&utm_campaign=neurogenesis-and-the-septotemporal-axis-at-sfn11 New neurons in the adult brain. How they work and what they're good for. Sat, 27 Apr 2013 19:09:46 -0600 http://wordpress.org/?v=2.8.5 hourly 1 By: Saving the best for the end: neurogenesis, plasticity and memory. #SFN11 | Functional Neurogenesis http://www.functionalneurogenesis.com/blog/2011/11/neurogenesis-and-the-septotemporal-axis-at-sfn11/comment-page-1/#comment-5564 Saving the best for the end: neurogenesis, plasticity and memory. #SFN11 | Functional Neurogenesis Thu, 17 Nov 2011 05:19:51 +0000 http://www.functionalneurogenesis.com/blog/?p=1348#comment-5564 [...] that returns me to a state of inner peace: ACSF-LTP. Yes, I plagiarized that last line from my previous post. We all know about LTP right? The ability of synapses to strengthen their connections in response [...] [...] that returns me to a state of inner peace: ACSF-LTP. Yes, I plagiarized that last line from my previous post. We all know about LTP right? The ability of synapses to strengthen their connections in response [...]

]]> By: Jason Snyder http://www.functionalneurogenesis.com/blog/2011/11/neurogenesis-and-the-septotemporal-axis-at-sfn11/comment-page-1/#comment-5540 Jason Snyder Wed, 16 Nov 2011 05:59:50 +0000 http://www.functionalneurogenesis.com/blog/?p=1348#comment-5540 Glad I could help you feel like you're at the conference! I don't have a clear answer to your questions - stress can certainly interfere with learning but it is also essential at the same time (perhaps depending on the amount of stress). Your novel situations idea is also interesting to me because there have been some great studies showing that in some seemingly unstressful situations (novel environment), animals actually are undergoing significant stress and if you remove that stress, the animals don't remember what they learned.... Glad I could help you feel like you’re at the conference! I don’t have a clear answer to your questions – stress can certainly interfere with learning but it is also essential at the same time (perhaps depending on the amount of stress). Your novel situations idea is also interesting to me because there have been some great studies showing that in some seemingly unstressful situations (novel environment), animals actually are undergoing significant stress and if you remove that stress, the animals don’t remember what they learned….

]]> By: Genecks http://www.functionalneurogenesis.com/blog/2011/11/neurogenesis-and-the-septotemporal-axis-at-sfn11/comment-page-1/#comment-5535 Genecks Wed, 16 Nov 2011 05:11:37 +0000 http://www.functionalneurogenesis.com/blog/?p=1348#comment-5535 Hello Professor Snyder, I was reading SfN 2011 blogs earlier today (I am unable to go, due to being a student finish his B.S. in Neuroscience), but I was lucky enough to come to this one later in the day. I'm trying to understand why you're discussing stress and learning as you do. I think most neuroscientists and cognitive psychologists already know that stress interferes with learning and recall. But a neurobiological explanation is still in the works. Also, as I've been reading more about learning and conditioning, it makes sense that novel situations can break habits and cause new learning (enhanced stimuli awareness and intake) to occur in some species, such as humans/primates. I guess, then, it's not really a stress hormone in that context, because it doesn't stress the individual? Anyone, nice read. This is the kind of read I was hoping to get out of people blogging about SfN. Thanks. Hello Professor Snyder,

I was reading SfN 2011 blogs earlier today (I am unable to go, due to being a student finish his B.S. in Neuroscience), but I was lucky enough to come to this one later in the day.

I’m trying to understand why you’re discussing stress and learning as you do. I think most neuroscientists and cognitive psychologists already know that stress interferes with learning and recall. But a neurobiological explanation is still in the works.

Also, as I’ve been reading more about learning and conditioning, it makes sense that novel situations can break habits and cause new learning (enhanced stimuli awareness and intake) to occur in some species, such as humans/primates. I guess, then, it’s not really a stress hormone in that context, because it doesn’t stress the individual?

Anyone, nice read. This is the kind of read I was hoping to get out of people blogging about SfN. Thanks.

]]> By: Jason Snyder http://www.functionalneurogenesis.com/blog/2011/11/neurogenesis-and-the-septotemporal-axis-at-sfn11/comment-page-1/#comment-5511 Jason Snyder Mon, 14 Nov 2011 22:41:42 +0000 http://www.functionalneurogenesis.com/blog/?p=1348#comment-5511 Hey Ian - thanks for bringing up that point. I completely agree that what we often call "bad" effects of stress may actually not be so bad but instead serve a very useful function. <a href="http://www.ncbi.nlm.nih.gov/pubmed/20463226" rel="nofollow">This paper</a> by Oomen et al. is one example that always reminds me that stress, through "adaptive programming" can prepare the animal to better deal with stressful events in the future. Hey Ian – thanks for bringing up that point. I completely agree that what we often call “bad” effects of stress may actually not be so bad but instead serve a very useful function. This paper by Oomen et al. is one example that always reminds me that stress, through “adaptive programming” can prepare the animal to better deal with stressful events in the future.

]]> By: Ian Mahar http://www.functionalneurogenesis.com/blog/2011/11/neurogenesis-and-the-septotemporal-axis-at-sfn11/comment-page-1/#comment-5508 Ian Mahar Mon, 14 Nov 2011 21:32:18 +0000 http://www.functionalneurogenesis.com/blog/?p=1348#comment-5508 Excellent synopsis, thanks. I saw both posters, and it seems as if the interaction between stress, ventral hippocampal neurogenesis and affective/antidepressant behaviours is really becoming a fascinating research topic. One thing I'd note, though, is that "stress hormones have bad effects on behavior and neurogenesis in the context of social stress" might not be the best way to describe some of these results; these 'bad effects' could be evolutionarily conserved adaptive responses to stress, in that a little extra anxiety may not be a bad thing if your environment involves "getting beaten up by a big bully mouse and then having to constantly live next to him". That doesn't fully explain effects seen (in some studies) with the forced swim test, though, as increased behavioral despair (or 'giving up more quickly') doesn't seem like a very adaptive behavior for the most part. Anyway, great post! Excellent synopsis, thanks. I saw both posters, and it seems as if the interaction between stress, ventral hippocampal neurogenesis and affective/antidepressant behaviours is really becoming a fascinating research topic.
One thing I’d note, though, is that “stress hormones have bad effects on behavior and neurogenesis in the context of social stress” might not be the best way to describe some of these results; these ‘bad effects’ could be evolutionarily conserved adaptive responses to stress, in that a little extra anxiety may not be a bad thing if your environment involves “getting beaten up by a big bully mouse and then having to constantly live next to him”. That doesn’t fully explain effects seen (in some studies) with the forced swim test, though, as increased behavioral despair (or ‘giving up more quickly’) doesn’t seem like a very adaptive behavior for the most part. Anyway, great post!

]]> By: Lucas http://www.functionalneurogenesis.com/blog/2011/11/neurogenesis-and-the-septotemporal-axis-at-sfn11/comment-page-1/#comment-5506 Lucas Mon, 14 Nov 2011 20:22:33 +0000 http://www.functionalneurogenesis.com/blog/?p=1348#comment-5506 Great post. But don't think neurogen is doing anything! Jokes aside, I think it is very important to recognize the behavioral double dissociation in hpc realms, esp neurogenesis Bravo! Great post. But don’t think neurogen is doing anything! Jokes aside, I think it is very important to recognize the behavioral double dissociation in hpc realms, esp neurogenesis
Bravo!

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